Dear Exhibitor,

Improving patient safety is a priority health goal across the globe. The tools of therapeutic risk management and pharmacoepidemiology are basic to improving safety by maximizing patient benefits while minimizing risks to patients. Join us in Philadelphia for what promises to be a milestone in bridging these disciplines.

We invite you to be part of history! The International Society for Pharmacoepidemiology (ISPE) is sponsoring the 1^st International Conference on Therapeutic Risk Management in conjunction with the 19^th International Conference on Pharmacoepidemiology (ICPE). This joint meeting will be held August 21-24, 2003, at the Wyndham Franklin Plaza Hotel, Philadelphia, PA.

The ICPE is acknowledged as the preeminent international conference on pharmaco-epidemiology. The meeting provides a unique scientific forum to learn about the use and effects of drugs in large populations, identification of rare adverse effects of drugs, promotion of more-rational prescribing practices, and recognition of new therapeutic benefits of drugs. More than 600 prominent and influential epidemiologists, physicians, policy-makers, and researchers within industry, academia and government attend this meeting. This year ISPE is building on its reputation as a sponsor of outstanding educational programs by including therapeutic risk management issues and strategies in the agenda.

The ISPE Scientific Program Committee is working hard to make this conference the Society's biggest, best and most memorable yet! The Committee has assembled a renowned faculty representing distinguished leaders in pharmacoepidemiology and therapeutic risk management. Robert M. Califf, MD, promises to be insightful (and provocative) in the Keynote Address. Samuel Shapiro, MD, BCh, FRCP(E) will leave us with much to discuss in the Special Plenary Lecture. The agenda also will include oral presentations, workshops, symposia, and more than 300 poster presentations. [Visit the ISPE website www.pharmacoepi.org for the meeting agenda.]

Attendees look forward to learning how your products and services can help them perform their jobs better, more effectively, and more economically — and improve patient safety. You can't afford to miss this historical meeting!

I hope you will consider exhibiting at the ICPE. Space is limited; I encourage you to send in your application and payment today! Please contact the ISPE office (301-718-6500 or ISPE@paimgmt.com) if you have questions.

Sincerely,

Mark Epstein, ScD
Executive Secretary

ISPE Staff Contact

Tony Flemons, ISPE Exhibit Manager, 301-718-6500 or ISPE@paimgmt.com.

Conference Site

Wyndham Franklin Plaza Hotel
17th & Race Street
Philadelphia, PA 19103
Phone: 215-448-2000
Fax: 215-448-2864

Exhibit Dates & Hours — PRELIMINARY

Thursday, August 21	0800-1600	Set-Up
Friday, August 22	0600-0800 1000-1030 1230-1430	Move-In Exhibits Open Exhibits Open
Saturday, August 23	0700-0800 1000-1030 1200-1400 1530-1600	Exhibits Open Exhibits Open Exhibits Open Exhibits Open
Sunday, August 24	0700-0830 1000-1030 1200-1345 1345-1600	Exhibits Open Exhibits Open Exhibits Open Dismantle

Exhibit Space Rates (US Dollars)

Industry	$1500/booth
Government/Academia	$1000/booth

Assignment of Exhibit Space

ISPE assigns space on a two-tiered system: A) Point system: 1-point for each year participated as an exhibitor with ISPE, and 1-point for each space taken, and B) First-come, first-served. ISPE reserves the right to decline any application or prohibit an exhibit based on the criteria established for the meeting.

Badges

Each exhibit space includes 1-complimentary registration badge. This badge will allow entrance to all meeting sessions, the Thursday evening Welcome Reception, the Saturday evening social event, and all coffee breaks and lunches. BADGES ARE NOT TRANSFERABLE. Additional badges for representatives will be provided at a discounted registration rate.

Booth Rental Includes

One (1) Booth Identification sign
8'x10' with back drape.
3' side rail drape
Listing in final program.
One (1) complimentary exhibitor badges for company personnel. Additional personnel may register at a discounted rate.

Carpeting

The exhibit area (Conference Center Ballroom & Hall) of the Wyndham is carpeted.

Decorating/Booth Equipment

Names, addresses, and telephone/fax numbers of exhibitors will be sent to ISPE's decorating firm that will mail decorating, drayage, electrical and shipping information directly to the exhibitor.

Hotel Reservations

ISPE has reserved a block of rooms at a special meeting rate at the Wyndham Franklin Plaza Hotel. Exhibitors assume all responsibility for arranging and paying for their housing accommodations. Hotel reservations must be made directly with the Wyndham Franklin Plaza Hotel (215-448-2000). Please make your hotel reservations by July 29 to guarantee the discounted rate and availability of rooms. When making the reservation, please state that you are attending the International Conference on Pharmacoepidemiology or ISPE to ensure you receive the special discounted rates! Persons with disabilities should inform the hotel of any special services required.

Shipping Information

Complete shipping information will be included in your exhibitor service kit

Sound

Loud speakers, tape recorders, sound movies, etc. that interfere with adjoining exhibitors are not permitted.

Sponsorship Opportunities

Please contact Mark Epstein, ISPE Executive Director, at 301-718-6500 for more information about opportunities available to you.

NOTE:

Our experience has shown that often the person(s) who are staffing a booth and the person(s) who did the co-coordinating for the booth are not one and the same. Please ensure that whoever is on site, is aware of all the services that have been ordered (i.e.: phone & data lines, electrical etc) and has copies with them of all orders placed.

1. Assignment of Space: ISPE will determine exhibitor space assignment. Once space is approved, an exhibit can only be moved with the mutual consent of ISPE and the specified exhibitor. Exhibitors will be given directions for installing and dismantling exhibits. All displays must be set up at least one-hour prior (i.e., 0700) to the official opening of the meeting at 0800, Friday, August 22. Space not set up by that time may be reassigned by ISPE.

2. Payment: Payment in full is required with a completed application for exhibit space. A completed form and payment must be received by July 11 to ensure inclusion in the final program book. Exhibitors are responsible for special equipment and services.

3. Cancellations: Cancellations in writing received by ISPE on or before July 11, 2003 will receive the entire exhibitor fee less a $300.00 processing fee. No refunds will be made after July 11.

4. Care of Exhibit Space: Exhibitors must maintain and keep their exhibit space and the contracted space in good order, at their expense.

5. Insurance: In all cases, exhibitors wishing to insure their goods must do so at their own expense.

6. Protection of Exhibit Space: Nothing shall be posted, tacked, nailed, screwed, or otherwise attached to columns, walls, floors, or other parts of the hotel without the permission of ISPE and a representative of the hotel. Packing, unpacking, and assembly or exhibits shall be done in designated areas and conform to instructions of ISPE or hotel representatives.

7. Default Occupancy: An exhibitor who fails to occupy contracted space is not relieved of the obligation to pay for such space at the full rental price, and ISPE shall have the right to use that space.

8. Use of Space: Exhibits will be permitted in the official exhibit area established by ISPE. Exhibitors shall not distribute printed matter, samples, or souvenirs, except from rented space. There shall be no sales of any kind, for neither cash or credit, for immediate or future delivery, nor shall there be any order taking.

9. Cancellation or Relocation of Meeting: If cancellation or relocation of meeting is due to circumstances within ISPE's control, ISPE's liability will be limited to a refund of fees to the exhibitor. If ISPE has no control over the cancellation or relocation, ISPE will have no liability of any kind, but may at its discretion, refund any fees paid by the exhibitor.

10. Liability: ISPE does not assume any responsibility for the protection or safety of the exhibitor, its official, agents, or employees. ISPE does not assume any responsibility for the protection of property of the exhibitor or their representatives, or of the property used in connection with the exhibit, from theft, damage, or destruction. Small or easily portable articles shall be properly secured or removed after exhibit hours and placed in safekeeping by the exhibitor. The exhibitor agrees to hold ISPE from all such claims and claims of liability of any kind arising from the activities of the exhibitors, its representatives, or from the display or use of property of the exhibitor. ISPE shall not be liable for the exhibitor for failure to provide space to an exhibitor if non-delivery is due to destruction to the building or the exhibit space.

11. Violation of Condition: The following actions shall constitute a violation of "Conditions of the Exhibitor Agreement": 1) violation of any municipal, state, or national laws, rules, or regulations, including safety codes; and 2) failure to follow procedures prescribed in Sections 1-10.

12. Distribution of Printed Material: Distribution of materials by exhibitors or their agents is limited to the area rented by the exhibitor. Flyers or other printed material may NOT be delivered to hotel rooms of ISPE registrants without advance permission from the Hotel. Any costs for such authorized distribution shall be the sole responsibility of the exhibitor. Other than the above, advertising circulars, brochures, etc. may only be distributed from exhibit booths, and may not be placed in any meeting room or in the ISPE registration area.

13. Exhibitor Seminars, Lectures, Food Functions, Etc: As a condition of receiving exhibit space, the Exhibitor agrees not to conduct sponsor, or promote any general seminars, lectures, or clinics in the same geographical area (within a radius of 50 miles) for a period of three days following the annual meeting.

14. Food or Beverage in Exhibitor Booths: No food, beverages or tobacco products of any type may be sold or distributed from an exhibitor booth.

15. Price List: Advertisements, exhibit materials or promotion may include prices, but shall not make price comparisons with competitive products.

16. Removal of Exhibits by ISPE: ISPE has the right to prohibit, bar, prevent and remove any exhibit or proposed exhibit, or any part or portion thereof, which in the judgment of ISPE is unsuitable or inappropriate for the exhibition. Such right shall extend to, but shall not be limited to, all equipment, materials, displays, installations or other items or things consisting of, part of, or used or distributed in connection with such exhibit. Specific punitive actions may be taken against companies that are determined by ISPE to have violated any provision of these rules and regulations. If an exhibitor's display is not erected by 5:00pm on August 21, 2003, ISPE will authorize the official contractor to install the display in order that the empty containers can be removed from the exhibit area for storage.

17. Security: ISPE will also furnish guard protection at night in the exhibit area, but neither the management of the facility, ISPE, the decorator nor their agents shall be responsible for any personal injury to the exhibitor, his agents, or for the safety of exhibits against robbery, damage by fire, accidents, or other causes.

18. Selling of Products or Services: All transactions must be conducted in a manner consistent with the professional nature of the exhibits.

19. Violation of Condition: The following actions shall constitute a violation of "Conditions of the Exhibitor Agreement": 1) violation of any municipal, provincial, state, or national laws, rules, or regulations, including safety codes; and 2) failure to follow procedures prescribed in Sections 1-18.

20. Acceptance of Exhibit Contracts: ISPE may refuse space to any company or individual whose products or services, in judgment of ISPE, do not further the educational and/or scientific purposes of the annual meeting. ISPE also reserves the right to limit space to any company or individual whose product or service is not related to orthodontic practice. Each exhibitor must indicate on the contract the type of equipment or products to be displayed.

General Policy
ISPE encourages broad and active support from and participation by commercial and other proprietary interests in its activities, compatible with the protection of full scientific independence of the activity.

1. Policies regarding display and distribution of other commercial materials at the ICPE (annual meeting) and other ISPE meeting. Exhibitors will confine their proprietary activities and materials to the exhibits area/exhibit hall. Members wishing to distribute or display proprietary or other promotional information, e.g., announcements of new or forthcoming publications, upcoming meetings, or other services in which the member may be directly involved, will be encouraged to do so, but only in areas designed for this purpose. Such promotional materials will not be permitted to be displayed or otherwise distributed in the general meeting areas

2. Occupational recruiting and interviewing. Public meetings of ISPE, including the ICPE (annual meeting), provide useful occasions for job market activities. Posting regarding availabilities and opportunities are encouraged, provided, however, that they will be limited to areas specifically designated for these purposes. At the annual meeting, ISPE will have a binder of resumes for those available for recruitment and a separate binder of postings for those actively offering job placements will be available at the registration desk.

3. Distribution of materials by exhibitors or their agents is limited to the area rented by the exhibitors.

   Flyers or other printed material may not be delivered to hotel rooms of ISPE registrants without advance permission from the hotel and ISPE. Any costs for such authorized distribution shall be the sole responsibility of the exhibitor. Other than the above, advertising circulars, brochures, etc. may only be distributed in the exhibit booths, and may not be place in any meeting room or in the registration area.

   Pre-meeting mailings to members or registrants may be undertaken only with the explicit permission of the ISPE Executive Committee and only upon receipt of specific proposals with rationale for pre-distribution, and payment of $750.00 (2003).

4. Exhibitor seminars, lectures. As a condition of receiving exhibit space, the Exhibitor agrees not to conduct, sponsor or promote any general seminars, lectures, or clinics in the same geographic area (within a radius of 50 miles) for a period of 3 days